Zombie Quel is a fast-paced survival shooter game where players must fight against zombies while avoiding traps to survive their endless battle for control of an island paradise. The main gameplay involves shooting at enemies and collecting items. The player can use various weapons, including guns that have different abilities such as fireballs or explosions in some levels like "Zombie Quel 3D".
Players usually start by gathering supplies from the games shop where they buy ammunition for their gun(s) to shoot zombies with more accuracy. The level design is designed so players can progress through each area of a new island, which grows larger and tougher as time goes on.